A group of nine European scientists involved in the use of fluoroquinolones has met to review and grade scientific literature on the subject.
The group, entitled REQUEST (REassessing QUinolones European Standards) was launched at the end of last year. The aim of REQUEST is to define guidelines for the appropriate use and prescription of fluoroquinolones among companion animals, and to publish recommendations which will help the veterinary practitioner in every day situations.
The group, chaired by Professor Jean-Pierre Cotard, met in March and discussed several topics including pharmacodynamics (spectrum and susceptibility results) and pharmacokinetics, current indications of fluoroquinolones and specificities of their use in cats and in dogs.
They also created a table to cross the indications where fluoroquinolones are a good opportunity with the assessment of available publications on diffusion, spectrum, clinical proof and protocol. On reviewing this table, it appears that for most indications (such as skin, urinary, respiratory infections) data is available and guidelines will be generated. For other tissue infections, there is a lack of data and further studies will be required before proposing any guidelines.
The meeting concluded with the creation of draft guidelines on fluoroquinolones and urinary tract infections of dogs. This draft, once validated and finalised, will be published as will subsequent documents developed at future meetings. The next meeting is due to take place at the end of the year in a European Veterinary University.
To ensure the independence of the experts, StratAdviser Ltd. has been charged with organising the European Expert Group and providing any scientific and methodological support. REQUEST is sponsored by Vétoquinol. Vétoquinol trades throughout five continents, having direct representation in 22 countries strongly involved in anti-infectives. |